Could Your Genes Be Affecting Your Heart Health?

It helps identify inherited cardiovascular risk.

High Lp(a) is one of the strongest inherited risk factors for cardiovascular disease. If you have a family history of heart disease or stroke—particularly at a younger age—testing may provide valuable insight into your long-term risk.

One test is usually enough.

Unlike many other health markers, Lp(a) levels are largely established in early childhood and remain relatively stable throughout life. In most cases, a single measurement provides a reliable assessment of your inherited risk.

It isn’t included in routine cholesterol screening.

A standard lipid profile measures total cholesterol, LDL, HDL, and triglycerides—but Lp(a) is not routinely tested. This means you may have normal cholesterol levels while still carrying an increased inherited cardiovascular risk.

Healthy habits are still important—but they may not lower Lp(a).

Regular exercise, a balanced diet, and maintaining a healthy weight are essential for heart health, but they have little effect on inherited Lp(a) levels. Researchers are currently studying new treatments specifically designed to reduce Lp(a).

Knowing your risk helps guide prevention.

If your Lp(a) level is elevated, your doctor can work with you to optimise other modifiable cardiovascular risk factors, including LDL cholesterol, blood pressure, blood sugar, inflammation (such as hs-CRP), weight, and overall metabolic health. Early identification allows for a more personalised approach to reducing long-term cardiovascular risk.